Computational sensing of herpes simplex virus using a cost-effective on-chip microscope

Compact and Cost-effective Lensless Tomographic On-chip Microscope

We present a field-portable lens-free optical tomographic microscope, which enables sectional-imaging of a large sample volume (~20 mm) with an axial-resolution of <7 μm. This platform, weighing ~110 grams, employs cost-effective lightemitting diodes and an optoelectronic sensor array to record in-line projection holograms of objects placed on a sensor-chip along different directions of illumin...

Herpes Simplex Virus Meningoencephalitis in A Methamphetamin User

Herpes Simplex Virus and Langerhans Cell Histiocytosis

Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such as Epstein-Barr virus (EBV, Human Herpes virus -4</...

Water Quality Management Using a Cost-effective and Field-portable Lensfree On-chip Microscope

We investigate the use of a high-throughput, compact and light-weight (~46grams) lensfree microscope for detection and enumeration of pathogenic waterborne parasites (e.g., Giardia Lamblia and Cryptosporidium Parvum) at lowconcentration levels. This field-portable platform operates based on lensfree inline-holography and achieves a resolution of ~1.5μm over a wide field-of-view (FOV) of ~24mm. ...

Detection of Herpes Simplex Virus Antibodies Using the Whole Virus and Recombinant gD

Background and Aims: Herpes simplex virus type 1 (HSV1) remains a potentially serious health problem world wide. All infected people, including asymptomatic ones, are potential sources for virus transmission. Virus envelope contains at least 13 glycoproteins, which glycoprotein D is the major target of immune responses. The aim of this study was development of a specific method that is a more...